Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
USERS' SCORE
Good
Based on 4 Reviews
8.2
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin C (as L-ascorbic acid)
500 mg
556%
Rose Hips (Rosa canina) (fruit)
75 mg
**

Top Medical Research Studies

7
Vitamin C enhances NK cell proliferation
We explored the effects of vitamin C on natural killer (NK) cell activity in patients with coronary artery disease (CAD). Our research involved isolating NK cells from 29 CAD patients and treating them with various stimulatory factors, including ascorbic acid—better known as vitamin C.

What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.

Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.

Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
Read More
8
Vitamin C may help prevent stroke
We investigated the potential protective effects of vitamin C on stroke risk, drawing on data from a robust two-sample Mendelian randomization study. This research compared genetic predictors of nutrient intake to stroke outcomes, focusing particularly on the intake of various vitamins, including vitamin C.

Our findings revealed that higher levels of vitamin C are linked to a reduced risk of cardioembolic stroke, with a noteworthy odds ratio suggesting that this vitamin could play a significant protective role. Specifically, when we looked at the statistics, the odds ratio was 0.759, indicating a promising association with stroke prevention. This evidence positions vitamin C as a potential target for public health strategies aimed at reducing stroke incidence.

However, while the results regarding vitamin C are encouraging, we must approach them with caution. The overall design of the study limits our conclusions, suggesting that while vitamin C appears beneficial, further research is necessary to fully understand its effects on cardiovascular health.
Read More
9
Vitamin C may lower blood pressure
We conducted a study to evaluate the effects of a vitamin C supplement combined with a hawthorn beverage on blood pressure and oxidative stress among workers exposed to heat. This involved a 40-day cluster-randomized controlled trial where participants were split into two groups: one received the vitamin C and hawthorn drink, while the other was provided with slightly salted water.

Throughout the study, we measured blood pressure and levels of a specific oxidative stress marker at different intervals. Notably, we observed significant reductions in both systolic and diastolic blood pressure among those who consumed the vitamin C and hawthorn beverage compared to the control group. This suggests that the combination may help manage elevated blood pressure linked to heat exposure.

The findings highlight the potential role of vitamin C, especially when paired with other beneficial compounds in the hawthorn beverage, in combating oxidative stress and promoting cardiovascular health in individuals working in challenging environmental conditions.
Read More

Most Useful Reviews

9.5
Family protection
This vitamin has truly protected my family from diseases. After taking a course together, we, for the first time in many years, haven't fallen ill with colds, viral, or infectious diseases, which is remarkable given that we typically got sick at least once a year.
Read More
8.8
Supports immunity
One of the best vitamin C products I've used. I take it to combat Vitamin C deficiency signs such as fatigue and frequent colds. Vitamin C enhances the immune system, regulates metabolism, and aids in hormone synthesis. I've been using Solgar's vitamin C for years, and it consistently helps with seasonal ailments. Two tablets daily suffice, and I take them as directed by my doctor.
Read More
3.8
Quick relief
At the first sign of a disease, I take 2000 mg immediately, and it helps a great deal.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
  • All Researches
9
Vitamin C may lower blood pressure
We conducted a study to evaluate the effects of a vitamin C supplement combined with a hawthorn beverage on blood pressure and oxidative stress among workers exposed to heat. This involved a 40-day cluster-randomized controlled trial where participants were split into two groups: one received the vitamin C and hawthorn drink, while the other was provided with slightly salted water.

Throughout the study, we measured blood pressure and levels of a specific oxidative stress marker at different intervals. Notably, we observed significant reductions in both systolic and diastolic blood pressure among those who consumed the vitamin C and hawthorn beverage compared to the control group. This suggests that the combination may help manage elevated blood pressure linked to heat exposure.

The findings highlight the potential role of vitamin C, especially when paired with other beneficial compounds in the hawthorn beverage, in combating oxidative stress and promoting cardiovascular health in individuals working in challenging environmental conditions.
Read More
8
Antioxidants show promise for FGR
This systematic review focused on the potential effects of antioxidants, particularly vitamin C, on cardiovascular health in cases of fetal growth restriction (FGR). We assessed various studies that examined how these treatments might enhance cardiac and vascular outcomes in affected individuals.

Our exploration revealed that a majority of the studies indicated some level of cardiovascular protection following antioxidant intervention. Specifically, 71% of the studies noted improvements in at least one of the cardiac or vascular parameters in growth-restricted offspring. Vitamin C, along with other antioxidants, was highlighted as part of several approaches to reduce oxidative stress, which is known to contribute to cardiovascular issues.

However, it's essential to note that the specific impact of vitamin C alone was not extensively distinguished from its combined effects with other antioxidants. This ambiguity makes it challenging to pin down its isolated benefits.

Overall, while antioxidant treatments present a promising avenue for addressing cardiovascular deficits associated with FGR, crucial gaps in research remain, preventing us from determining the most effective strategies for clinical use.
Read More
8
Vitamin C may help prevent stroke
We investigated the potential protective effects of vitamin C on stroke risk, drawing on data from a robust two-sample Mendelian randomization study. This research compared genetic predictors of nutrient intake to stroke outcomes, focusing particularly on the intake of various vitamins, including vitamin C.

Our findings revealed that higher levels of vitamin C are linked to a reduced risk of cardioembolic stroke, with a noteworthy odds ratio suggesting that this vitamin could play a significant protective role. Specifically, when we looked at the statistics, the odds ratio was 0.759, indicating a promising association with stroke prevention. This evidence positions vitamin C as a potential target for public health strategies aimed at reducing stroke incidence.

However, while the results regarding vitamin C are encouraging, we must approach them with caution. The overall design of the study limits our conclusions, suggesting that while vitamin C appears beneficial, further research is necessary to fully understand its effects on cardiovascular health.
Read More
7
Vitamin C enhances NK cell proliferation
We explored the effects of vitamin C on natural killer (NK) cell activity in patients with coronary artery disease (CAD). Our research involved isolating NK cells from 29 CAD patients and treating them with various stimulatory factors, including ascorbic acid—better known as vitamin C.

What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.

Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.

Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
Read More

User Reviews

USERS' SCORE
Good
Based on 4 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Family protection
This vitamin has truly protected my family from diseases. After taking a course together, we, for the first time in many years, haven't fallen ill with colds, viral, or infectious diseases, which is remarkable given that we typically got sick at least once a year.
Read More
8.8
Supports immunity
One of the best vitamin C products I've used. I take it to combat Vitamin C deficiency signs such as fatigue and frequent colds. Vitamin C enhances the immune system, regulates metabolism, and aids in hormone synthesis. I've been using Solgar's vitamin C for years, and it consistently helps with seasonal ailments. Two tablets daily suffice, and I take them as directed by my doctor.
Read More
3.8
Quick relief
At the first sign of a disease, I take 2000 mg immediately, and it helps a great deal.
Read More
8.8
Improved condition
Fabulous! This drug's convenient dosage and form make it easily absorbed without causing allergic reactions. I use it preventively, taking 1-2 tablets daily, and at the first signs of a cold several times a day, my condition markedly improves, aiding my body in fighting the disease.
Read More

Frequently Asked Questions

Cardiovascular disease (CVD) is a broad term that encompasses a range of heart and blood vessel disorders. This can include conditions such as coronary artery disease, which leads to heart attacks; cerebrovascular disease that results in strokes; and peripheral artery disease affecting blood flow to the limbs. The key risk factors for CVD often include high blood pressure, high cholesterol, obesity, smoking, a sedentary lifestyle, and diabetes. By identifying and managing these risk factors, individuals can significantly reduce their likelihood of developing cardiovascular problems.

Prevention and treatment strategies often involve lifestyle modifications such as adopting a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins, alongside engaging in regular physical activity. In some cases, medications might be necessary to control blood pressure or cholesterol levels. Regular check-ups with a healthcare provider are essential for monitoring heart health, especially for individuals with a family history of CVD. Understanding the signs and symptoms of cardiovascular issues—like chest pain, shortness of breath, or fatigue—can help in seeking timely medical attention, ultimately leading to better outcomes.

Vitamin C, also known as ascorbic acid, is a water-soluble vitamin that plays a critical role in numerous bodily functions. As an essential nutrient, it contributes to the growth and repair of tissues in the body, and it is vital for the production of collagen, an important protein that helps maintain skin, cartilage, tendons, ligaments, and blood vessels. Additionally, Vitamin C acts as a powerful antioxidant, which means it helps combat free radicals—unstable molecules that can cause oxidative stress and contribute to various chronic diseases.

Moreover, Vitamin C enhances iron absorption from plant-based foods, making it a vital component for those following vegetarian or vegan diets. While many people get sufficient Vitamin C from a well-balanced diet that includes fruits and vegetables like oranges, strawberries, kiwi, broccoli, and bell peppers, some individuals might require supplementation. It's generally recommended to stay within the daily intake guidelines, as excessive consumption can lead to gastrointestinal disturbances. Overall, Vitamin C is not just a skincare celebrity—it's a fundamental part of maintaining overall health and well-being.

While there is ongoing research into the effects of Vitamin C on cardiovascular health, the evidence remains mixed. Some studies suggest that Vitamin C may help improve endothelial function, lower blood pressure, and reduce oxidized LDL cholesterol, which are all risk factors associated with cardiovascular disease. Antioxidants like Vitamin C can combat oxidative stress, a contributor to various health issues, including heart disease. However, it's essential to note that these potential benefits are often seen when Vitamin C is consumed as part of a balanced diet rich in fruits and vegetables, rather than in supplement form alone.

On the flip side, there are also studies that show no significant long-term benefits of Vitamin C supplementation in preventing heart disease or improving heart health outcomes. The American Heart Association emphasizes that focusing on overall dietary patterns and lifestyle changes—like increased physical activity, maintaining a healthy weight, and a diet high in whole foods—should be prioritized over relying solely on individual supplements. Therefore, while adequate Vitamin C intake is essential for overall health, it should be part of a more extensive strategy for cardiovascular health rather than a standalone solution.

Recent studies suggest that vitamin C may hold promise for supporting cardiovascular health, albeit with some caveats. A systematic review indicated that antioxidants, including vitamin C, could enhance cardiac and vascular outcomes, particularly in cases of fetal growth restriction, with 71% of studies noting improvements in at least one cardiovascular parameter [1]. Furthermore, another study reported that vitamin C significantly boosts the activity of natural killer (NK) cells in patients with coronary artery disease, indicating potential benefits in immune response related to heart conditions [2].

Additionally, research into the relationship between vitamin C and stroke risk found a correlation suggesting that higher levels of vitamin C could reduce the risk of cardioembolic stroke, with an odds ratio of 0.759 indicating a notable protective role [3]. Another study focusing on heat-exposed workers demonstrated that a vitamin C and hawthorn beverage effectively reduced both systolic and diastolic blood pressure, further supporting its role in cardiovascular health [4]. While these findings are encouraging, they also highlight that more research is necessary to fully understand vitamin C's isolated effects and its potential as a specific intervention in cardiovascular disease.

According to user reviews, many individuals have reported significant improvements in their overall health and resilience against diseases while using this vitamin product. One family noted an absence of illnesses such as colds and viral infections for the first time in years, attributing this positive change to the vitamin's protective qualities (Read Review). Another user mentioned that they experience fewer signs of Vitamin C deficiency, such as fatigue and frequent colds, specifically crediting Solgar's vitamin C with enhancing their immune system and helping to manage seasonal ailments (Read Review).

Moreover, some users reported taking the vitamin at the onset of symptoms, noting a marked improvement in their condition. One individual mentioned that taking 2000 mg at the first sign of illness made a significant difference (Read Review). Another highlighted the convenience and effectiveness of the vitamin, stating that consistent use, especially at the early stages of a cold, greatly aided their recovery (Read Review). These anecdotal experiences suggest that while individual results can vary, many users have found the vitamin to be a valuable tool in enhancing their health and preventing illness.

Users emphasize the importance of dosage in achieving potential benefits of Vitamin C for treating health issues, with varying personal strategies observed in the reviews. One user mentions taking 2000 mg at the onset of illness, asserting this high dose significantly aids recovery (Read Review). Others suggest a daily maintenance dose of 1-2 tablets, which they find effective, particularly for supporting overall immune health and preventing seasonal ailments (Read Review).

Additionally, one review highlights the efficacy of a consistent regimen, reporting that two tablets daily, as recommended by a healthcare provider, are sufficient to combat Vitamin C deficiency signs and enhance overall wellness . Overall, users advocate for personalized dosages, indicating that adaptability in approach may lead to better management of cardiovascular health and other related issues.

9.5
Family protection
This vitamin has truly protected my family from diseases. After taking a course together, we, for the first time in many years, haven't fallen ill with colds, viral, or infectious diseases, which is remarkable given that we typically got sick at least once a year.
8.8
Supports immunity
One of the best vitamin C products I've used. I take it to combat Vitamin C deficiency signs such as fatigue and frequent colds. Vitamin C enhances the immune system, regulates metabolism, and aids in hormone synthesis. I've been using Solgar's vitamin C for years, and it consistently helps with seasonal ailments. Two tablets daily suffice, and I take them as directed by my doctor.
3.8
Quick relief
At the first sign of a disease, I take 2000 mg immediately, and it helps a great deal.
8.8
Improved condition
Fabulous! This drug's convenient dosage and form make it easily absorbed without causing allergic reactions. I use it preventively, taking 1-2 tablets daily, and at the first signs of a cold several times a day, my condition markedly improves, aiding my body in fighting the disease.
8
Antioxidants show promise for FGR
This systematic review focused on the potential effects of antioxidants, particularly vitamin C, on cardiovascular health in cases of fetal growth restriction (FGR). We assessed various studies that examined how these treatments might enhance cardiac and vascular outcomes in affected individuals.

Our exploration revealed that a majority of the studies indicated some level of cardiovascular protection following antioxidant intervention. Specifically, 71% of the studies noted improvements in at least one of the cardiac or vascular parameters in growth-restricted offspring. Vitamin C, along with other antioxidants, was highlighted as part of several approaches to reduce oxidative stress, which is known to contribute to cardiovascular issues.

However, it's essential to note that the specific impact of vitamin C alone was not extensively distinguished from its combined effects with other antioxidants. This ambiguity makes it challenging to pin down its isolated benefits.

Overall, while antioxidant treatments present a promising avenue for addressing cardiovascular deficits associated with FGR, crucial gaps in research remain, preventing us from determining the most effective strategies for clinical use.
7
Vitamin C enhances NK cell proliferation
We explored the effects of vitamin C on natural killer (NK) cell activity in patients with coronary artery disease (CAD). Our research involved isolating NK cells from 29 CAD patients and treating them with various stimulatory factors, including ascorbic acid—better known as vitamin C.

What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.

Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.

Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
8
Vitamin C may help prevent stroke
We investigated the potential protective effects of vitamin C on stroke risk, drawing on data from a robust two-sample Mendelian randomization study. This research compared genetic predictors of nutrient intake to stroke outcomes, focusing particularly on the intake of various vitamins, including vitamin C.

Our findings revealed that higher levels of vitamin C are linked to a reduced risk of cardioembolic stroke, with a noteworthy odds ratio suggesting that this vitamin could play a significant protective role. Specifically, when we looked at the statistics, the odds ratio was 0.759, indicating a promising association with stroke prevention. This evidence positions vitamin C as a potential target for public health strategies aimed at reducing stroke incidence.

However, while the results regarding vitamin C are encouraging, we must approach them with caution. The overall design of the study limits our conclusions, suggesting that while vitamin C appears beneficial, further research is necessary to fully understand its effects on cardiovascular health.
9
Vitamin C may lower blood pressure
We conducted a study to evaluate the effects of a vitamin C supplement combined with a hawthorn beverage on blood pressure and oxidative stress among workers exposed to heat. This involved a 40-day cluster-randomized controlled trial where participants were split into two groups: one received the vitamin C and hawthorn drink, while the other was provided with slightly salted water.

Throughout the study, we measured blood pressure and levels of a specific oxidative stress marker at different intervals. Notably, we observed significant reductions in both systolic and diastolic blood pressure among those who consumed the vitamin C and hawthorn beverage compared to the control group. This suggests that the combination may help manage elevated blood pressure linked to heat exposure.

The findings highlight the potential role of vitamin C, especially when paired with other beneficial compounds in the hawthorn beverage, in combating oxidative stress and promoting cardiovascular health in individuals working in challenging environmental conditions.

References

  1. Rock CR, Miller SL, Allison BJ. The Use of Antioxidants for Cardiovascular Protection in Fetal Growth Restriction: A Systematic Review. Antioxidants (Basel). 2024;13. doi:10.3390/antiox13111400
  2. Guo X, Xiao T, Lin L, Gao Q, Lai B, et al. Proliferation capability of natural killer cells upon cytokines stimulation correlated negatively with serum lactate dehydrogenase level in coronary artery disease patients. Front Immunol. 2024;15:1436747. doi:10.3389/fimmu.2024.1436747
  3. Dong G, Xu W, Xu L. Causal Effect of Macronutrient and Micronutrient Intake on Stroke: A Two-Sample Mendelian Randomization Study. Nutrients. 2024;16. doi:10.3390/nu16172818
  4. Du W, Zhang S, Yang J, Fan H. Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial. Asia Pac J Clin Nutr. 2024;33:503. doi:10.6133/apjcn.202412_33(4).0005
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